Search on: KINASE, TBETAR-II 
Descriptors Found: 1
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Descriptor English:   Receptor, Transforming Growth Factor-beta Type II 
Descriptor Spanish:   Receptor Tipo II de Factor de Crecimiento Transformador beta 
Descriptor Portuguese:   Receptor do Fator de Crescimento Transformador beta Tipo II 
Synonyms English:   Kinase, TbetaR-II
Receptor, Transforming Growth Factor beta Type II
TGF beta Type II Receptor
TGF beta Type II Receptors
TGF-beta Type II Receptor
TGF-beta Type II Receptors
TGFBR2
TbetaR II Kinase
TbetaR-II Kinase
Transforming Growth Factor beta Type II Receptor
Transforming Growth Factor beta Type II Receptors
Transforming Growth Factor-beta Type II Receptor
Transforming Growth Factor-beta Type II Receptors
Type II TGF beta Receptor
Type II TGF beta Receptors
Type II TGF-beta Receptor
Type II TGF-beta Receptors  
Tree Number:   D08.811.913.696.620.682.700.795
D12.776.543.750.705.852.720.750
D12.776.543.750.750.400.820.875
Definition English:   A transmembrane serine-threonine kinase that forms a heteromeric complex with TYPE I TGF-BETA RECEPTORS when bound to TGF-BETA. This receptor complex regulates a variety of physiological and pathological processes including CELL CYCLE ARREST; CELL PROLIFERATION; CELL DIFFERENTIATION; WOUND HEALING; EXTRACELLULAR MATRIX production, immunosuppression and ONCOGENESIS. 
History Note English:   2019 (1993) 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   57594 
Unique Identifier:   D000077294 

Occurrence in VHL:
 

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